TABLE 1.

Overview of previous studies (n > 100) investigating the impact of endometriosis or endometriosis‐related pain on daily life

Author, year	Sample Size	Objective, Characteristics assessed	Main findings
Barbara et al. (2017)	210 women with endometriosis	Mental health in women with endometriosis.	Not only pelvic pain, but also individual characteristics (i.e. self‐esteem, body esteem and emotional self‐efficacy), time since diagnosis and intimate relationship status influence psychological health in women with endometriosis.
Bernays et al. (2020)	565 women with endometriosis, 565 control women	Sexual activity, dysmenorrhoea, dyspareunia, chronic pain and infertility were evaluated for their associations with different sexual activities.	Women with endometriosis report lower frequencies of petting, foreplay and vaginal intercourse. Dyspareunia is negatively associated with sexual activity.
Chen et al. (2016)	10,439 women with endometriosis, 10,439 control women	Endometriosis as a risk factor for depression and anxiety disorders.	Endometriosis was associated with an increased risk for depression and anxiety disorders.
De Graaff et al. (2013)	931 women with endometriosis	Effect of endometriosis on education, work and social wellbeing. Impact of endometriosis‐associated symptoms on health‐related quality of life.	Endometriosis affected work, relationships and quality of life. Comorbidities, chronic pain and dyspareunia negatively influenced physical and mental health.
De Graaff et al. (2016)	83 women with endometriosis with 74 partners, 40 control women with 26 partners	Association between endometriosis and its related physical and mental symptoms with sexual functioning in women and male partners.	Dyspareunia and depressive symptoms are associated with impaired sexual functioning in women with endometriosis, whereas sexual functioning in their male partners is not affected.
Facchin et al. (2015)	78 women with endometriosis with pelvic pain, 32 women with endometriosis without pelvic pain, 61 control women	Impact of endometriosis and pelvic pain on mental/physical quality of life, anxiety and depression.	Pelvic pain led to poorer quality of life and mental health. No difference between asymptomatic endometriosis and control group. Dysmenorrhoea had significant effects only on physical activity of life, non‐menstrual pelvic pain affected all variables, no significant effects were found for dyspareunia and dyschezia.
Fourquet et al. (2010)	108 women with symptomatic endometriosis	Impact of endometriosis‐related pain and/or co‐existing symptoms on daily life activities (household chores, child care, sexual relationships, studies, appetite, exercise, sleeping, work and social life)	Symptoms disrupted all aspects of daily life. Menstrual pain, incapacitating pain, abdominal pain and depression were identified as predictors of poor performance at work and home. Incapacitating pain and dyspareunia predict impairments in social and sexual aspects of life.
Lorencatto et al. (2006)	100 women with endometriosis (44 of which have chronic pelvic pain)	Prevalence of depression in women with endometriosis with and without pelvic pain.	Depression is highly prevalent in women with endometriosis, especially those with pelvic pain.
Nnoaham et al. (2011)	745 women with endometriosis (587 of which were symptomatic), 673 control women	Impact of endometriosis on health‐related quality of life (HRQoL) and work productivity.	Physical HRQoL was significantly reduced in affected women compared with women with similar symptoms but no endometriosis. Women with endometriosis showed greater work productivity loss compared with symptomatic control women. Pelvic pain and disease severity are major drivers for work productivity loss in endometriosis.
Schliep et al. (2015)	190 women with endometriosis, 147 women with other gynecologic pathology, 136 control women	Description of pain characteristics in women with endometriosis compared with other or no pelvic pathology in women receiving laparoscopy	More cyclic pelvic pain, chronic pain, dyspareunia, dysmenorrhoea and dyschezia was reported in women with endometriosis compared with women with other or no gynaecological pathology.
Sperschneider et al. (2019)	505 women with endometriosis, 505 control women	Association between endometriosis/disease symptoms and professional life.	Endometriosis is associated with impairment of professional life. Chronic pain was significantly associated with increased sick leave and loss of productivity.
Vercellini et al. (2012)	100 women with rectovaginal endometriosis, 100 women with peritoneal and/or ovarian endometriosis, 100 control women	Impact of rectovaginal endometriosis on dyspareunia and sexual functioning.	Women with endometriosis experience more frequent and more severe deep dyspareunia as well as worse sexual functioning. Differences between diverse endometriosis forms were marginal.