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This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license.
A–G, CNAs can be detected utilizing off-target CAPP-seq reads in the plasma of Ewing sarcoma, rhabdomyosarcoma, and osteosarcoma. These findings are confirmed by CAPP-seq of the tumor in a subset of patients (right side of A–D).