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. 2022 Jul 22;17(7):e0270126. doi: 10.1371/journal.pone.0270126

Table 3. Odds ratios (ORs) and 95% confidence intervals (CIs) for obstructive lung pattern based on free thyroxine quartiles.

fT4 quartile
Q1
(0.89–1.09 ng/dL)
(n = 294, 23.4%)
Q2
(1.10–1.19 ng/dL)
(n = 321, 25.5%)
Q3
(1.20–1.30 ng/dL)
(n = 317, 25.2%)
Q4
(1.31–1.76 ng/dL)
(n = 329, 25.9%)
Obstructive pattern
Model 1
Model 2
Model 3
Model 4
1.000
1.000
1.000
1.000
1.984 (0.864, 4.556)
1.944 (0.819, 4.614)
2.041 (0.817, 5.095)
1.998 (0.797, 5.011)
2.898 (1.326, 6.334)
2.777 (1.246, 6.189)
2.818 (1.243, 6.389)
2.875 (1.265, 6.535)
3.664 (1.731, 7.754) *
2.878 (1.322, 6.268)
3.000 (1.340, 6.716)
2.970 (1.287, 6.854)

fT4, free thyroxine.

Model 1, unadjusted; Model 2, with adjustment for age and sex; Model 3 as model 2, with additional adjustment for occupation, smoking, alcohol consumption, walking activity, and body mass index; Model 4 as model 3, with additional adjustment for glycated hemoglobin, and thyroid-stimulating hormone.

OR and 95% CI for risk of obstructive lung pattern were estimated using logistic regression models. All p values and 95% CI for OR were corrected by Bonferroni’s method due to multiple testing.

*p<0.001,

†0.001≤p<0.01.