. 2022 Jul 6;11:e67464. doi: 10.7554/eLife.67464

Table 1. Voltage-dependence of activation and inactivation, and time course of inactivation of Cav2.3 co-transfected with α2δ1 and different β subunits in tsA-201 cells.

Table 1—source data 1. Source data for data shown in Table 1.

β-subunit	Cav2.3 - Activation 2 mM Ca²⁺						Cav2.3 - Inactivation 2 mM Ca²⁺
β-subunit	V_0.5[mV]	k[mV]	V_rev[mV]	act thresh[mV]	current density[pA/pF]	n	V_{0.5, inact}[mV]	k_inact[mV]	plateau[%]	n
no β					–10.7±1.1	23
β2a	–14.8±1.2	4.8±0.2	37.1±0.9	–32.0±0.9	–130.0⁺⁺⁺±15.2	26	–40.6±1.6	7.3±0.5	0.4±1.1	13
_C3S/C4Sβ2a	–13.9±1.7	4.7±0.3	38.2±1.1	–30.9±0.7	–105.7⁺⁺⁺±21.4	12	–62.6***^/###/§§§±1.6	8.3^##±0.4	3.8±1.6	9
β2d	–15.9^§±1.1	4.6±0.2	37.2±1.1	–32.1^§±0.7	–107.7⁺⁺⁺±13.4	17	–69.9***^/###±2.0	8.2^##±0.2	2.0±0.7	10
β2e	–14.1±0.9	4.8±0.2	40.3*±0.6	–31.5±0.7	–96.8⁺⁺⁺±14.3	32	–39.9±1.9	6.5±0.3	3.8±1.2	24
β3	–10.5±0.7	5.2±0.2	39.8±0.9	–29.2±0.7	–64.6⁺⁺±12.8	17	–76.2***^/###±1.0	7.0±0.1	4.1±0.7	14
β4	–13.1±0.7	5.0±0.2	38.5±0.5	–31.0±0.5	–74.8⁺⁺⁺±11.9	17	–70.3***^/###±1.2	7.5±0.1	2.4±0.4	11
Cav2.3–5 s Inactivation time course 2 mM Ca²⁺
β-subunit	r50 [%]	r100 [%]	r250 [%]	r500 [%]	r1000 [%]	r5000 [%]	n
β2a	71.3±2.1	52.4±2.8	27.8±2.9	14.3±2.3	6.5±1.2	1.3±0.3	17
_C3S/C4Sβ2a	67.4^§§§/%±5.2	47.3^#/§§§/%%±6.4	23.4^§±5.3	11.6±3.3	6.2±1.7	3.4±1.1	11
β2d	57.4*^/###/§§§±2.8	32.6***^/###/§§±2.4	11.3*^/###±1.7	4.4**^/###±0.9	2.4**^/###±0.6	1.7±0.5	21
β2e	77.5±2.9	64.2±3.3	41.1±3.2	22.3±2.8	10.1±2.0	3.3±0.8	27
β3	32.9***^/###±2.9	14.2***^/###±1.5	6.1***^/###±1.0	4.4**^/###±0.7	2.9^#±0.5	1.6±0.3	16
β4	50.3***^/###/§§±2.7	27.1***^/###±2.5	8.6**^/###±1.4	3.7**^/###±0.8	2.0**^/###±0.5	1.0±0.2	15