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. 2022 Feb 25;31(14):2452–2461. doi: 10.1093/hmg/ddac024

Table 1.

Chromosome positions, nearest genes, allele frequencies and imputation accuracies of COVID-19 variants related to risk of respiratory failure among Black and white ARIC participants

rsID Chr:position* Proximal gene(s) Non-coded Risk Black freq Black R2 White freq White R2 OR**
rs11385942 3:45834967 SLC6A20, LZTFL1, CCR9, FYCO1, CXCR6, XCR1 G GA; A 0.052 0.99 0.081 1.00 1.77
rs657152 9:133263862 ABO C A 0.431 0.98 0.378 0.96 1.48
rs10735079 12:112942203 OAS1, OAS2, OAS3 A G 0.226 N/A 0.350 N/A 1.3
rs2109069 19:4719431 DPP9 G A 0.213 0.90 0.304 0.80 1.4
rs74956615 19:10317045 TYK2 A T 0.009 0.88 0.056 0.88 1.6
rs2236757 21:33252612 IFNAR2 G A 0.215 0.98 0.299 0.98 1.3

*Based on Genome Reference Consortium Human Build 38

Risk allele

* * Reported by previous GWASs (6,7)

Abbreviations: rsID = reference single nucleotide polymorphism cluster identification number; Chr = chromosome; freq = frequency; R2 = index for imputation accuracy