Fig. 2.

Significant clusters in the group per time interaction contrast. Left: Red range scale displays decrease over time of thalamic connectivity in recent-onset psychosis (ROP) compared to controls (no suprathreshold clusters). Blue range scale displays increase over time of thalamic connectivity in ROP compared to controls. All results are corrected using an initial cluster-defining threshold of p < 0.001 at voxel-level and a subsequent cluster-extent FDR correction at p < 0.05. Right: Boxplot showing z-transformed averaged connectivity values per group and time (baseline or 12 months) from the significant cluster of the left figure (peak at x, y, z = +28, +56, +22).