Table 1.
Socio-demographic and clinical characteristics of recent-onset psychosis and healthy controls at baseline and after 1 year
| Baseline |
Follow-up (1 year) |
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|---|---|---|---|---|---|---|---|---|
| ROP | HC | Stats | p value | ROP | HC | Stats | p value | |
| n | 124 | 87 | 42 | 40 | ||||
|
| ||||||||
| Mean age at baseline scan (s.d.) | 19.8 (4.1) | 19.7 (3.7) | T(193.9) = −0.110 | 0.913 | 19.4 (3.5) | 18.8 (3.7) | T(79.0) = −0.763 | 0.447 |
|
| ||||||||
| Gender (% male) | 72.6% | 59.8% | χ2(1) = 3.253 | 0.071 | 64.3% | 65.0% | χ2(1)<0.1 | ~1 |
|
| ||||||||
| Ethnicity (% Caucasian) | 70.2% | 60.5% | χ2(1) = 1.722 | 0.189 | 69.0% | 62.5%% | χ2(1) = 0.154 | 0.695 |
|
| ||||||||
| Handedness (% right) | 93.0% | 95.1% | T(80.873) = 0.42972 | 0.690 | 87.5% | 94.1% | T(26.9) = 0.638 | 0.529 |
|
| ||||||||
| Education, years (s.d.) | 12.2 (2.4) | 13.2 (3.3) | T(147.97) = 2.473 | 0.015 | 12.0 (2.1) | 12.5 (3.5) | T(63.3) = 0.668 | 0.506 |
|
| ||||||||
| Parental education, years (s.d.) | 14.7 (2.7) | 14.7 (3.3) | T(74.6) = 0.113 | 0.910 | 14.2 (2.9) | 15.1 (3.6) | T(31.0) = 0.864 | 0.394 |
|
| ||||||||
| Affective psychosisa (%) | 21.5% | NA | 23.8% | NA | ||||
|
| ||||||||
| DUP, days (s.d.) | 183 (140) | NA | 182 (125) | NA | ||||
|
| ||||||||
| Time since psychosis onset: mean days; s.d. (range) | 134; 93 (30–241) | NA | 123; 92 (35–240) | NA | ||||
|
| ||||||||
| At baseline | At follow-up | |||||||
|
| ||||||||
| GAF (s.d.) | 47.3 (11.0) | 85.9 (8.0) | T(181.42) = 28.187 | <0.001 | 56.5 (12.0) | 86.0 (7.6) | T(85.0) = 14.1 | <0.001 |
|
| ||||||||
| SAPS total (s.d.) | 4.0 (3.6) | NA | 2.4 (2.8) | NA | ||||
|
| ||||||||
| SANS total (s.d.) | 9.5 (4.1) | NA | 7.2 (4.4) | NA | ||||
ROP, recent-onset psychosis; HC, healthy controls; GAF, Global Assessment of Function; BPRS, Brief Psychiatric Rating Scale; SAPS, Scale for the Assessment of Positive Symptoms; SANS, Scale for the Assessment of Negative Symptoms.
a
Affective psychosis includes bipolar disorder and major depressive disorder with psychotic features.