Table 2.
Clusters showing between-group significant differences In thalamic connectivity
| k | Peak MNI (x, y, z) | T at peak | Region (voxels) | Aal (voxels) | BA (voxels) |
|---|---|---|---|---|---|
| ROP > HC | |||||
| 8328 | 54, 8, −16 | 6.295 | Right STG (1919), precentral G. (1767), MTG (742), MeFG (644), parahippocampal G. (517), postcentral G. (407), uncus (189), MFG (119), Insula (91) | Right temporal sup. (1462), precentral (988), postcentral (511), temporal pole sup. (463), temporal pole mid (423), hippocampus (367), rolandic operc (365), temporal mid (334), parcentral L. (312), parahippocampal (281), supp. motor area (173), amygdala (130), fusiform (113), frontal mid (63). left paracentral L. (571), postcentral (234), supp. motor area (98), precuneus (85), | 6 (832), 4 (393), 21 (298), 22 (292), 38 (235), 3 (183), 43 (56), 13 (54), 42 (53), 34 (46), 28 (40), 41 (39), 44 (28), 20 (23), 5 (18) |
| 6570 | −50, −2, −16 | 5.878 | Left STG (2102), MTG (1211), precentral G. (821), parahippocampal G. (453), insula (171), uncus (154), inf. parietal L. (121), amygdala (113), postcentral G (106), transverse temporal G (86), hippocampus (62) | Left temporal mid (1515), temporal sup (1505), postcentral L (331), hippocampus (325), rolandic operc (287), temporal pole sup (263), temporal inf (263), temporal pole mid (195), amygdala (122), fusiform (99), parahippocampal (90) | 21 (379), 22 (284), 6 (202), 38 (174), 41 (108), 13 (102), 4 (98), 42 (91), 43 (56), 20 (52), 28 (31), 44 (28), 34 (27), 40 (21) |
| 336 | 30, −58, 14 | 4.760 | Right MTG (27) | Right calcarine (75), precuneus (12) | NA |
| 129 | −26, −70, 14 | 4.405 | Left MTG (19), precuneus (10) | NA | NA |
| 116 | 34, −50, −8 | 3.868 | Parahippocampal G. (65), fusiform G. (40) | Right fusiform (100), | 37 (28), 19 (23) |
| 109 | 48, −52, 4 | 3.869 | Right MTG (81), STG (28) | Right temporal mid (69) | 39 (4) |
| 103 | −8, −22, 10 | −4.326 | Left thalamus (101) | Left thalamus (103) | NA |
| HC > ROP | |||||
| 846 | −38, −50, −50 | −4.932 | Left cerebellum post. lobe (815), cerebellar tonsil (284), pyramis (212), tuber (159), uvula (72), declive (65) | Left cerebellum crus1 (316), crus2 (319), 8 (105), 7b (90) | NA |
| 345 | 24, 52, 16 | −4.225 | Right SFG (146), MFG (80), MeFG (61) | Right frontal sup (179), frontal mid (56) | 10 (45), 32 (6) |
| 178 | 4, 16, 14 | −4.362 | Left ant cingulate (1), corpus callosum (105) | NA | NA |
| 94 | 12, −50, −46 | −3.856 | Right cerebellum post. lobe (65), tonsil (65), nodule (26), cerebellum ant. lobe (29) | Right cerebellum 9 (84), vermis 9 (10) | NA |
ROP, recent-onset psychosis; HC, healthy controls; BA, Brodmann area; STG, superior temporal gyrus; G, gyrus; sup, superior; MTG, middle temporal gyrus; MFG, middle frontal gyrus; MeFG, medial frontal gyrus; L, lobule.
Results are corrected using an initial cluster-defining threshold of p < 0.001 at voxel-level and a subsequent cluster-extent FDR correction at p < 0.05.