Table 3. Timeline.

Date	Main report/symptoms	Comments	Prescription
First consultation. May 2020	Nausea for 1 month, vomiting, weakness, prostration, headache in temples, occipital pain radiating to head, profuse perspiration during sleep, unrefreshing sleep, vertigo when looking up; cold hands during the night unless wearing long sleeves. Water seems too sweet. Desire for squid. Generally worse in the mornings. Yearns for recreation, but cannot even walk; motion aggravates her. Sensitive to odours. Planning a Caesarean section for delivery ‘to avoid suffering’.	Strategy for repertorisation and prescribing: totality of symptoms repertorised with VithoulkasCompass Repertory 6.0. The patient's level of health (Vithoulkas): 2–3, group A. 15	Sepia officinalis , 14 doses of LM2 and later LM3. The patient described herself, by text message, as feeling “a million times better after taking the medicine for 10 days”. Therefore reducing the frequency of intake was advised, but symptoms returned, so she continued taking the medicine.
Follow-ups (FUs) FU1: at 5 weeks FU2: at 7.5 weeks FU3: at 11.5 weeks	Improvement of symptoms: slept longer hours; cessation of flushes of perspiration; nausea only on empty stomach—reported during FU1 over the phone. Old complaints of neck pain have returned; appearance of sleepiness. Physically active. Slight swelling in ankles, better by morning. Loss of hair; bleeding gums, appearance of metallic taste. Eruption on face (Hering's law). Walking, cycling and attending fitness regularly again. Blood pressure: 126/66 (the first measurement during the treatment was 98/54); no vertigo. Desire for soda water.	No initial aggravation—as usual with LM potencies. New minor transient symptoms: loss of hair; bleeding gums, appearance of metallic taste. An old symptom has reappeared: old complaints of neck pain. Reaction to the medicine—Observation No. 4 (Vithoulkas) after centesimal potencies: 15 there is local and general amelioration, but new symptoms belonging to the given remedy have appeared in the patient; no evident initial aggravation.	The single homeopathic medicine Sepia officinalis in LM5 potency was prescribed for 21 days. After gradual general improvement, a placebo of one globule per day was prescribed, and Sepia officinalis in LM6 potency was taken from time to time in between.
FU4 for acute state. November 2020	The rapid antigen test is positive for COVID-19. Headache pressing outward above eyebrows; left-sided nose obstruction and clear discharge, loss of smell; nausea if a meal is delayed; anxiety after testing positive for COVID-19; fears parents could die; longs for physical activity even in this acute state; desire for chocolate; heat in hands. No more swelling in ankles.	Repertorisation of new acute symptoms with Radar Repertory has led to the same unipotent homeopathic medicine. Differential diagnoses: sinusitis (ICD: J01.1) and COVID-19 (ICD: UO7.2).	Sepia officinalis LM6 continued every day.
FU5: at 1 week; FU 6: at 2.5 weeks	Nose obstruction is better. Generally much better 5 days later; smell returned 90%; improvement of all symptoms. Appearance of sciatica, ameliorated by pressure. Looking forward to not having a natural delivery. Complains that fitness centres for exercise in pregnancy are closed down due to lockdown.	No initial aggravation—as usual with LM potencies. The new leg pain might have arisen due to late anatomical changes in pregnancy or the evolution of events due to Hering's law. The approximate reaction to the medicine—Observation No. 3 (Vithoulkas) after centesimal potencies: the patient is much better in almost every aspect, but still has some problems, 15 though without the appearance of an evident initial aggravation.	Sepia officinalis LM6 was continued. Due to sciatica, one sip was taken from the third glass (90% of the spoonful of medicine diluted in the first glass of water was poured away, refilled and the process repeated once more) every 20 minutes, three times, in order to relieve the pain on the first day, followed by placebo.
FU7: at 4.5 weeks	No immediate amelioration of the sciatica. She feels that physiotherapy helped to relieve 90% of the pain. Successful planned delivery of a healthy baby by Caesarean section at 3.5 weeks. Started breastfeeding; post-partum problems with profuse perspiration and hot flushes during the night; started adding infant milk formula.	No sciatica after delivery.	Sepia officinalis LM8—14 doses.
FU8: at 6.5 weeks	11 days after the prescription, no waking from flushes of perspiration any more; scanty leucorrhoea; happy with her weight. Says she will not be able to stay off work for long. Tearful three times for no reason. Has stopped breastfeeding.	Improvement of the burdensome symptoms after delivery. Appearance of a proving symptom 15 —weeping without knowing why.	Continued with Sepia officinalis LM9 and later LM10 daily; asked to decrease the frequency as symptoms have faded.