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. 2022 May 23;28(7):1377–1380. doi: 10.1038/s41591-022-01874-4

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 2 — The Ministry of Health monitors respiratory viruses, including SARS- CoV-2, using genomic surveillance in sentinel centers. Surveillance uses non-probabilistic sampling of SARS-CoV-2 infections focusing on variants of concern (VOC) and variants of interest (VOI) through traveler (imported cases) and community surveillance (hospitalized cases and national core priority studies). The samples are sent for whole-genome sequencing (WGS) and genotyping across the country. Between December 22, 2020, and February 21, 2022, 70,186 SARS-CoV-2 samples were analyzed. Of these, 28.6% (n=20,088) were sequenced and 71.4% (n=50,098) assessed by detection of variant-associated mutations (VAM) using RT- PCR. Of these analyzed samples, 85.3% (n=59,891) correspond to VOC and 5.2% (n=3,618) to variants of interest (VOI).