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. 2022 Jul 19;16:224–228. doi: 10.1016/j.artd.2022.06.003

Table 3.

Perioperative TXA usage: subgroup analysis.

Patients receiving TXA (n = 405) CTKA (n = 146)
RATKA (n = 259)
P value
Mean, std dev Mean, std dev
Hb (gm/dl) POD1 10.8 ± 1.3 10.9 ± 1.3 .35a
Δ Hb (gm/dl, preoperative−POD1) 2.5 ± 1.1 2.5 ± 1.0 .99a
Largest Δ Hb (gm/dl)c 3.1 ± 1.1 3.0 ± 1.1 .78a
Blood transfusion, n (%) .59b
 Yes 1 (0.7%) 1 (0.4%)
 No 145 (99.3%) 258 (99.6%)
Patients not receiving TXA (n = 81) CTKA (n = 41)
RATKA (n = 40)
P value
Mean, std Mean, std
Hb (gm/dl) POD1 10.4 ± 1.3 10.4 ± 1.5 .99a
Δ Hb (gm/dl, preoperative−POD1) 2.6 ± 1.2 2.6 ± 1.1 .99a
Largest Δ Hb (gm/dl)c 3.2 ± 1.2 3.4 ± 1.3 .51a
Blood transfusion, n (%) .36b
 Yes 1 (2.4%) 3 (7.5%)
 No 40 (97.6%) 37 (92.5)

Hb, hemoglobin; std dev, standard deviation; TXA, tranexamic acid.

a

t-test

b

Pearson’s chi square Test.

c

Preoperative Hb value−lowest Hb values within 2 d postoperatively.