Table 5.

Weighted distribution of outcomes calculated from the cohorts reported in Tables 4 and 7

Outcome	Population	N. of cohorts	Mean ± sd	Median (IQR)
GFR reduction	Pediatric cohorts [4, 7, 17, 22, 30, 31, 34, 48, 62–66]	13	8.7 ± 12.3%	5.6% (8.8%)
GFR reduction < 90 ml/min/1.73 m2	Pediatric cohorts [4, 7, 22, 30, 31, 34, 62, 63, 66]	9	11.5 ± 15.9%	10.7% (11.0%)
GFR reduction < 60 ml/min/1.73 m2	Pediatric cohorts [17, 48, 64, 65]	4	4.4 ± 2.3%	4.8% (2.9%)
GFR reduction	Adult cohorts [38, 39, 67–69]	5	26.9 ± 10.6%	25.4% (17.7%)
Proteinuria/albuminuria	Pediatric cohorts [4, 7, 17, 22, 31, 34, 48, 62–65]	11	7.6 ± 5.8%	6.2% (9.4%)
	Adult cohorts [38, 39, 67–69]	5	29.0 ± 21.0%	43.0% (24.0%)
Hypertension	Pediatric cohorts [4, 7, 17, 22, 30, 31, 34, 48, 62–66]	13	7.1 ± 8.1%	5.0% (6.3%)
	Adult cohorts [38, 39, 67–69]	5	29.0 ± 22.6%	32.2% (14.6%)
ABPM hypertension	Pediatric cohorts [28, 37, 70–75]	8	28.0 ± 9.7%	31.1% (13.0%)
ABPM masked hypertension	Pediatric cohorts [28, 37, 70, 72, 74, 75]	6	14.3 ± 11.9%	19.9% (19.4%)

In square brackets: references

Legend: GFR glomerular filtration rate, ABPM ambulatory blood pressure monitoring