Table 5.

Outputs using the MetaIntegrator statistical method

Parameter	Description
effectSize	Summary effect size computed using a random effect model
effectSizeStandardError	Standard error for the summary effect size
effectSizePval	Given summary effect size and standard error, p-value calculated based on a standard normal distribution
effectSizeFDR	Benjamini-Hochberg FDR correction for multiple hypothesis testing
tauSquared	Inter-dataset variation as estimated by the DerSimonian-Laird method
numStudies	Number of studies in which the gene was present
cochranesQ	Cochrane’s Q value for evaluating heterogeneity of effect size estimates between studies
heterogeneityPval	p-value of Cochrane’s Q calculated against a chi-squared distribution
fisherStatUp	Log sum of p-values that each up-regulated gene using Fisher’s method
fisherPvalUp	p-value under a chi-squared distribution
fisherFDRUp	Benjamini-Hochberg FDR correction for multiple hypothesis testing
fisherStatDown	Log sum of p-values that each gene is down-regulated using Fisher’s method
fisherPvalDown	p-value under a chi-squared distribution
fisherFDRDown	Benjamini-Hochberg FDR correction for multiple hypothesis testing