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. 2022 Jul 22;13:4237. doi: 10.1038/s41467-022-31103-y

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — a Overall differentially expressed genes’ counts after silencing Piezo1 (si-P1), Piezo2 (si-P2), Piezo1 and Piezo2 (si-P1+2). b Log₂-fold changes for top 14 genes involved in the GO term- “positive regulation of secretion by cell” compared si-Piezo1 to si-Ctrl. c The relative mRNA expression of the identical top 7 DE genes as in b, from cells of after silencing of Piezo1 (si-Piezo1, n = 4), silencing of Cartpt (si-Cartpt, n = 4), and double silencing of both (si-P1+Cartpt, n = 4). Data are presented as box Tukey plot, and the definition of box Tukey is as indicated as in Fig. 1.