Skip to main content
. 2022 Jul 22;5:103. doi: 10.1038/s41746-022-00630-9

Table 2.

Mortality hazard ratios per 10-year increment in AEE in the combined data of the Sleep Heart Health Study, the Wisconsin Sleep Cohort, and the MrOS Sleep Study.

Cox Model 1 HR (95% CI) Cox Model 2 HR (95% CI) Cox Model 3 HR (95% CI)
All-cause (a) Central EEG 1.12 (1.07–1.17) 1.15 (1.10–1.20) 1.11 (1.06–1.16)
(b) EEG+EOG+EMG 1.11 (1.06–1.17) 1.17 (1.11–1.24) 1.14 (1.08–1.20)
(c) ECG 1.08 (1.04–1.12) 1.09 (1.06–1.13) 1.07 (1.03–1.11)
(d) Respiratory 1.04 (1.00–1.09) 1.10 (1.04–1.16) 1.09 (1.03–1.15)
(e) Ensemble–Avg. 1.23 (1.15–1.31) 1.38 (1.28–1.49) 1.29 (1.20–1.39)
Cardiovascular (a) Central EEG 1.21 (1.11–1.32) 1.24 (1.14–1.36) 1.17 (1.07–1.28)
(b) EEG+EOG+EMG 1.13 (1.03–1.25) 1.21 (1.09–1.34) 1.15 (1.04–1.28)
(c) ECG 1.15 (1.08–1.22) 1.16 (1.09–1.24) 1.11 (1.04–1.19)
(d) Respiratory 1.04 (0.95–1.13) 1.09 (0.97–1.22) 1.07 (0.96–1.19)
(e) Ensemble–Avg. 1.36 (1.20–1.54) 1.58 (1.37–1.83) 1.40 (1.21–1.62)

The mortality analysis was performed with (n = 9386, deaths = 3045) for all-cause mortality and (n = 9188, death = 976) for cardiovascular mortality. HR hazard ratio, AEE age estimate error. Model 1: age. Model 2: age, sex, body mass index, race, smoking status, education level, daily alcohol intake, daily caffeine intake, benzodiazepines, sedatives, antidepressants, and cohort. Model 3: Model 2 + wake after sleep onset, N2%, REM%, arousal index, apnea-hypopnea index, sleep time with blood oxygen saturation below 80%, Epworth Sleepiness Scale Score, hypertension, congestive heart failure, history of heart attack, stroke, and type 2 diabetes.