Table 4.
Joint effects of lifestyle behaviors on NAFLD and advanced fibrosis
| Multivariable adjusted OR (95% CI) | NAFLD Multivariable-adjusted OR (95% CI) |
Advanced fibrosis Multivariable-adjusted OR (95% CI) |
|---|---|---|
| Low PA/High Sed (Reference) | ||
| Low PA/Mid Sed | 0.86 (0.31, 2.36) | 0.80 (0.20, 3.20) |
| Low PA/Low Sed | 0.63 (0.23, 1.73) | 0.74 (0.10, 5.73) |
| Mid PA/High Sed | 0.37 (0.19, 0.72) | 1.35 (0.21, 8.54) |
| Mid PA/ Mid Sed | 0.80 (0.42, 1.49) | 0.46 (0.14, 1.55) |
| Mid PA/Low Sed | 0.47 (0.25, 0.86) | 2.01 (0.39, 10.37) |
| High PA/ High Sed | 0.66 (0.34, 1.28) | 0.43 (0.03, 5.29) |
| High PA/ Mid Sed | 0.73 (0.36, 1.50) | 1.86 (0.40, 8.74) |
| High PA/ Low Sed | 0.27 (0.10, 0.69) | 0.27 (0.07, 1.06) |
| Combined HEI & total energy | ||
| Low HEI/High Total Energy (Reference) | ||
| Low HEI/Mid Total Energy | 0.96 (0.33, 2.89) | 0.20 (0.05, 0.93) |
| Low HEI/Low Total Energy | 2.42 (1.07, 5.50) | 2.45 (0.54, 11.24) |
| Mid HEI/High Total Energy | 0.87 (0.42, 1.82) | 1.88 (0.50, 7.16) |
| Mid HEI/Mid Total Energy | 0.78 (0.29, 2.11) | 1.18 (0.20, 6.99) |
| Mid HEI/Low Total Energy | 0.59 (0.19, 1.82) | 0.12 (0.02, 0.95) |
| High HEI/High Total Energy | 1.35 (0.56, 3.28) | 0.36 (0.08, 1.74) |
| High HEI/Mid Total Energy | 0.71 (0.34, 1.48) | 0.05 (0.01, 1.38) |
| High HEI/Low Total Energy | 0.83 (0.49, 1.40) | 0.42 (0.13, 1.33) |
Notes:
Abbreviations: NAFLD: non-alcoholic fatty liver disease, OR: odds ratio, CI: confidence interval, PA: physical activity, Sed: sedentary behavior, HEI: Healthy Eating Index 2015;
Low, Med, High refer to Tertiles 1, 2, and 3, respectively;
Models: Multivariable logistic regression;
Values: Multivariable-adjusted Odds Ratios (95% Confidence Intervals);
Combined physical activity & sedentary behavior model adjusted for age, sex, metabolic syndrome and total energy;
Combined HEI & total energy model adjusted for age, sex, metabolic syndrome, physical activity and alcohol use.