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. 2022 Jul 22;12:12569. doi: 10.1038/s41598-022-16276-2

Table 3.

Relationship between the alcohol flushing response and depression according to alcohol intake (< 5 g/day, 5–14.9 g/day, 15–29.9 g/day, ≥ 30 g/day) (n = 139,380).

Alcohol intake (g/day) Alcohol flushing status AOR (95% CI) P-value
 < 5 Never flusher 1 (Ref.)
Former flusher 1.07 (0.81–1.41) 0.644
Current flusher 1.20 (1.07–1.35) 0.002
5–14.9 Never flusher 1 (Ref.)
Former flusher 1.06 (0.64–1.75) 0.821
Current flusher 1.39 (1.13–1.70) 0.002
15–29.9 Never flusher 1 (Ref.)
Former flusher 1.00 (0.59–1.71) 0.987
Current flusher 1.26 (0.95–1.67) 0.109
 ≥ 30 Never flusher 1 (Ref.)
Former flusher 0.85 (0.49–1.47) 0.559
Current flusher 0.97 (0.76–1.24) 0.814

AOR, adjusted odds ratio; CI, confidence interval; Ref, reference.

OR adjusted for sex, age, social activity, family income level, educational level, smoking status, age of drinking onset, and attempts to reduce/quit drinking.