Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jul 22;13(7):640. doi: 10.1038/s41419-022-05063-6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 5 — A Kaplan–Meier curves of human PDAC patients with SENP3 high or low. B Gene Sets Enrichment Assay (GSEA) is used to analyze RNA sequence data of PDAC patients from TCGA database. The list shows the top pathways upregulated in SENP3 high vs. SENP3 low and shows that chemokine signaling and TCR signaling-related genes were enriched in SENP3 high patients. C Heatmaps show that immune response-related genes are positively related to SENP3 expression level in PDAC patients from TCGA database. D Heatmaps show that immune response-related genes are a positive correlation with SENP3 expression levels in p53 mutant PDAC patients from TCGA database. E The high mRNA level of CCL5 and CD8A is shown in SENP3 high PDAC patients with p53 mutant but not the patients with p53 wild type.