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NMDA is composed of a highly homologous extracellular amino-terminal (ATD), a bilobal ligand-binding domain (LBD), three transmembrane regions, a membrane helix (MD) composed of a reentrant ion pore-lining ring, and a more dispersed intracellular carboxy-terminal domain (CTD). Picture excerpt from Vyklicky et al (PDB code 4TLM).
