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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Neuroimage. 2022 Apr 30;256:119267. doi: 10.1016/j.neuroimage.2022.119267

Fig. 5.

Fig. 5.

Reduced vmPFC–Hippocampal Connectivity in Older Adults

(A) In an exploratory seed-based PPI analysis, we examined age-related differences in connectivity with vmPFC. We found that older adults exhibited reduced vmPFC connectivity with a hippocampal (HPC) cluster extending into the amygdala during reciprocate relative to defect outcomes (Thresholded: https://identifiers.org/neurovault.image:512046; Unthresholded: https://identifiers.org/neurovault.image:512074). (B) Interrogation of this hippocampal cluster revealed that the pattern was stable across all partner types. We note that Z statistic images were thresholded parametrically (Gaussian Random Field Theory) using clusters determined by Z>3.1 and a (corrected) cluster significance threshold of P=.05.