1. Characteristics of skin ulcer at baseline.

Study	Ulcer size PRP (cm2)	Ulcer size control (cm2)	Time of ulcer PRP (weeks)	Time of ulcer control (weeks)
Anitua 2008	5.5	27.6	68.0	110.0
Driver 2006	4.0	22.0	‐	‐
Kakagia 2007	28.4	28.9	20.0	19.0
Knighton 1990	11.6	109.7	119.0	47.0
Krupski 1991	13.0	10.8	22.0	24.8
Li 2012	‐	‐	6 (2‐13)	3 (2‐9)
Planinsek Rucigaj 2007	148.7	4.8	‐	‐
Senet 2003	13.7	5.7	202.4	280.0
Stacey 2000	5.1	8.9	24.0	24.0
Weed 2004	6.7	3.2	51.3	54.4

PRP: platelet‐rich plasma