Table 1.
Patient characteristics at index admission according to suPAR level
| Characterisitcs | All patients (N = 5124) | suPAR <3 ng/mL [n = 2738 (53.4%)] | suPAR 3–6 ng/mL [n = 1945 (38.0%)] | suPAR ≥6 ng/mL [n = 441 (8.6%)] |
|---|---|---|---|---|
| Demographics | ||||
| Female, n (%) | 2612 (51.0) | 1365 (49.9) | 1031 (53.0) | 216 (49.0) |
| Age (years), median (IQR) | 65.9 (50.5–76.9) | 59.1 (44.4–72.0) | 71.1 (58.6–80.4) | 71.4 (60.5–81.7) |
| Biomarkers | ||||
| suPAR (ng/mL), median (IQR) | 2.9 (2.2–4.1) | 2.2 (1.8–2.6) | 3.9 (3.4–4.6) | 7.6 (6.7–9.6) |
| eGFR (mL/min/1.73 m2), median (IQR) | 88.0 (75.3–102) | 92.2 (80.0–106) | 83.1 (71.3–96.8) | 80.9 (68.9–97.1) |
| CRP (mg/L), median (IQR) | 6.0 (2.0–28) | 3.0 (1.0–10) | 11 (3.0–49) | 31 (7.0–81) |
| Sodium (mEq/L), median (IQR) | 139 (136–141) | 139 (137–141) | 138 (135–140) | 136 (132–139) |
| Chronic disease status, n (%) | ||||
| Diabetes | 796 (15.5) | 326 (11.9) | 381 (19.6) | 89 (20.2) |
| Hypertension | 1782 (34.8) | 804 (29.4) | 792 (40.7) | 186 (42.2) |
| Cardiovascular disease | 1533 (29.9) | 726 (26.5) | 657 (33.8) | 150 (34.0) |
| Outcomes | ||||
| Length of stay (days), median (IQR) | 0.9 (0.4–3.9) | 0.7 (0.3–2.1) | 1.4 (0.5–5.1) | 2.6 (0.8–7.8) |
| Time to readmission (days), median (IQR) | 144 (35–378) | 170 (41–417) | 128 (32–338) | 84 (23–262) |