Table 6:
P-gp modulators (Lund, Terrier, FDA website) | |||
---|---|---|---|
Inhibitor | Inducer | ||
Strong Inhibitor | Cyclosporine | Strong Inducer | Carbamazepine |
Dronedarone | Rifampin | ||
Ketoconazole | St. John’s Wort167* | ||
Itraconazole | |||
Lapatinib | |||
Ritonavir | |||
Verapamil | |||
Weak Inhibitor | Amiodarone | Weak Inducer | Phenytoin |
Carvedilol | |||
Clarithromycin | |||
Diltiazem | |||
Eliglustat | |||
Fluvoxamine | |||
Maraviroc | |||
Mirabegron | |||
Paroxetine | |||
Propafenone | |||
Quinidine | |||
Ranolazine | |||
Simeprevir | |||
Saquinavir | |||
Ticagrelor | |||
Tipranavir | |||
Uncertain Inhibitor | Carbozantinib | ||
Enzlutamide | |||
Erythromycin | |||
Ibrutinib | |||
Imatinib | |||
Irbesartan | |||
Ivermectin | |||
Ledipasvir | |||
Lomitapide | |||
Loperamide | |||
Meflokine | |||
Ponatinib | |||
Regorafenib | |||
Simvastatin | |||
Tacrolimus |