Figure 6.

Regional differences in brain HRF

(A) Preparation for fiber photometry measurement of GCaMP and tdTomato signals in the left M1 and right CPu. Both have a direct anatomical connection with the right M1 receiving local micro-electrical stimulation.

(B) Confocal images showing expression of GCaMP and tdTomato in the M1 and CPu.

(C and D) Peri-stimulus heatmaps and response time courses of the changes in corrected GCaMP, derived HbO, derived HbR, and derived HbT and modeled HRFs in the M1 and CPu, respectively. Pie charts in the insets indicate the ratio between positive (red) and negative (blue) HRF polarities. All pre-stimulus heatmap color bars use the same unit as the time course y axis. Error bars represent standard deviation (4 subjects, 12 trials).

See also Figure S8.