Figure 2.
Significant accelerations in multiple epigenetic measures of aging occur in men over the course of initial HIV infection, but not in matched men who remain HIV-uninfected
Dot plots of HIV seroconverter (SC, n = 102) and persistently HIV seronegative (SN, n = 101) participants show the epigenetic change from the pre-HIV infection or equivalent visit (Visit A) to the post-HIV infection or equivalent visit (Visit B) within each participant as measured by (A) AAR, B) EEAA, (C) PEAA, (D) GEAA, and (E) aaDNAmTL. Heavy bar and numerical value = median change, whiskers = 25th-75th percentiles, p values = t-test for change within each participant group for differences from zero.