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. 2022 Jul 22;14:77. doi: 10.1186/s13073-022-01082-2

Fig. 2.

Fig. 2

CASR NM_000388.3:c.488C > G, p.(Pro163Arg). A Structure of the inactive form of CaSR (PDB 5k5t) around Pro163. Protein ribbon is coloured from N-terminal, blue, to C-terminal, red, except for Pro163 (carbon atoms coloured magenta); sidechain atoms of Pro163 and near neighbours are shown in stick format; the grey sphere shows a bound calcium ion. B As A, but showing the predicted structure of the p.(Pro163Arg) variant