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. 2022 Jul 22;16:24. doi: 10.1186/s40246-022-00399-8

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — TFs associated with co-expressed individual muscle promoter regions induced by exercise. Unsupervised analysis revealed 21 clusters of co-expressed individual promoter regions induced by exercise (b: before exercise). Each cluster includes data of 10 subjects and 4 time points; expression in each time point for each subject expressed by rank (the highest expression level: 4; the lowest: 1) and is presented as median and interquartile range. Denominator: the number of exercise-regulated individual muscle promoter regions at a time point; Numerator: the cluster size. The top enriched TFs are shown for each cluster