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. 2021 Oct 19;61(6):2483–2493. doi: 10.1093/rheumatology/keab775

Table 4.

Risk of developing future proliferative LN in patients with non-proliferative LN on biopsy 2

Biopsy 3
Biopsy 1 Non-proliferative Proliferative
 Non-proliferative, n (%) 7 (87.5) 1 (12.5)
 Proliferative, n (%) 7 (54) 6 (46)

Patients with non-proliferative (class I, II or V) on biopsy 2 who underwent a third biopsy (n = 21) were stratified according to the class of biopsy 1. Patients with proliferative LN on biopsy 1 who converted to non-proliferative LN on biopsy 2 were numerically more likely to reconvert to a proliferative class on the third biopsy as compared with those who had non-proliferative LN in both biopsy 1 and 2 (46% vs 12.5%; odds ratio: 6.0, 95% CI: 0.6, 64).