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. 2022 Apr 4;187(2):325–344. doi: 10.1093/toxsci/kfac037

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Figure 9. — Whole-animal proteomic comparison between wild-type (WT) and wfikkn1 mutant zebrafish at 48 hpf. A, PCA plot of 6 biological replicates of the wild-type (wt) and wfikkn1 (mut) significant peptides (false discovery rate [FDR] p < .05). B, Comparison between genes of proteins predicted from significant peptides (FDR p < .05; proteomics) and significant differentially expressed genes (FDR p < .05; transcriptomics). C, Heatmap showing MetaCore process networks (significant processes are bolded) on the y-axis, and proteins from proteomic and transcriptomic (*) datasets on the x-axis. Blue boxes represent proteins expressed in at least 3 biological replicates of WT or mutants and absent in all replicates of the other genotype.