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. 2022 May 24;36(4):1312–1321. doi: 10.1111/jvim.16430

TABLE 1.

Selected clinicopathological variables of cats with single measurement ionized hypercalcemia and normocalcemic cats at diagnosis of azotemic chronic kidney disease.

Variables Normocalcemic (n = 131) n Hypercalcemic (n = 33) n P
Median [25th, 75th percentile] Median [25th, 75th percentile]
Ionized calcium (mmol/L) 1.31 [1.28, 1.34] 131 1.41 [1.39, 1.50] 33
Age (years) 15.2 [13.0, 16.9] 128 15.2 [11.8, 17.1] 31 .95
Albumin (g/dL) 3.1 [2.9, 3.3] 131 3.1 [3.0, 3.3] 33 .65
ALP (U/L) 30 [23, 39] 131 31 [23, 37] 33 .38
BCS (1‐9) 4 [3, 5] 131 4 [3, 4] 33 .27
Calcidiol (pmol/L) 137 [109, 177] 34 134 1
Calcitriol (pmol/L) 424 [341, 456] 34 146 1
Chloride (mEq/L) 118 [116, 120] 129 118 [117, 122] 29 .15
Creatinine (mg/dL) 2.39 [2.13, 2.70] 131 2.38 [2.20, 2.74] 33 .91
FGF23 (pg/mL) 443 [265, 1015] 123 1608 [643, 2527] 29 .001
Globulin (g/dL) 4.6 [4.3, 5.1] 131 4.4 [4.1, 5.3] 33 .35
HCO3 (mEq/L) 20 [19, 22] 131 20 [18, 21] 33 .23
MMS (0‐2) 1 [1, 1] 127 1 [1, 1] 32 1
PCV (%) 35 [31, 38] 131 32 [30, 35] 33 .24
Venous pH 7.35 [7.32, 7.38] 131 7.34 [7.30, 7.37] 33 .68
Phosphate (mg/dL) 3.87 [3.50, 4.80] 131 4.12 [3.78, 4.86] 33 .38
Potassium (mEq/L) 4.0 [3.7, 4.3] 129 4.2 [3.9, 4.6] 29 .022
PTH (pg/mL) 19.6 [10.7, 37.5] 118 10.4 [2.6, 36.6] 27 .053
SBP (mmHg) 135 [124, 146] 131 137 [126, 151] 32 .53
Sex (n [%] male) 55 (42) 131 21 (64) 33 .042
Sodium (mEq/L) 153 [151, 155] 129 153 [150, 156] 29 .49
Total calcium (mg/dL) 10.0 [9.6, 10.3] 131 10.7 [10.3, 11.4] 33 <.001
Total protein (g/dL) 7.8 [7.4, 8.1] 131 7.6 [7.1, 8.3] 33 .31
USG 1.017 [1.015, 1.020] 81 1.018 [1.016, 1.020] 21 .25
Weight (kg) 3.70 [3.15, 4.45] 127 3.81 [3.18, 4.28] 31 .98

Abbreviations: ALP, alkaline phosphatase; BCS, body condition score; FGF23, fibroblast growth factor 23; MMS, muscle mass score; PTH, parathyroid hormone; SBP, systolic blood pressure; USG, urine specific gravity.