TABLE 1.
Variables | Normocalcemic (n = 131) | n | Hypercalcemic (n = 33) | n | P |
---|---|---|---|---|---|
Median [25th, 75th percentile] | Median [25th, 75th percentile] | ||||
Ionized calcium (mmol/L) | 1.31 [1.28, 1.34] | 131 | 1.41 [1.39, 1.50] | 33 | |
Age (years) | 15.2 [13.0, 16.9] | 128 | 15.2 [11.8, 17.1] | 31 | .95 |
Albumin (g/dL) | 3.1 [2.9, 3.3] | 131 | 3.1 [3.0, 3.3] | 33 | .65 |
ALP (U/L) | 30 [23, 39] | 131 | 31 [23, 37] | 33 | .38 |
BCS (1‐9) | 4 [3, 5] | 131 | 4 [3, 4] | 33 | .27 |
Calcidiol (pmol/L) | 137 [109, 177] | 34 | 134 | 1 | |
Calcitriol (pmol/L) | 424 [341, 456] | 34 | 146 | 1 | |
Chloride (mEq/L) | 118 [116, 120] | 129 | 118 [117, 122] | 29 | .15 |
Creatinine (mg/dL) | 2.39 [2.13, 2.70] | 131 | 2.38 [2.20, 2.74] | 33 | .91 |
FGF23 (pg/mL) | 443 [265, 1015] | 123 | 1608 [643, 2527] | 29 | .001 |
Globulin (g/dL) | 4.6 [4.3, 5.1] | 131 | 4.4 [4.1, 5.3] | 33 | .35 |
HCO3 − (mEq/L) | 20 [19, 22] | 131 | 20 [18, 21] | 33 | .23 |
MMS (0‐2) | 1 [1, 1] | 127 | 1 [1, 1] | 32 | 1 |
PCV (%) | 35 [31, 38] | 131 | 32 [30, 35] | 33 | .24 |
Venous pH | 7.35 [7.32, 7.38] | 131 | 7.34 [7.30, 7.37] | 33 | .68 |
Phosphate (mg/dL) | 3.87 [3.50, 4.80] | 131 | 4.12 [3.78, 4.86] | 33 | .38 |
Potassium (mEq/L) | 4.0 [3.7, 4.3] | 129 | 4.2 [3.9, 4.6] | 29 | .022 |
PTH (pg/mL) | 19.6 [10.7, 37.5] | 118 | 10.4 [2.6, 36.6] | 27 | .053 |
SBP (mmHg) | 135 [124, 146] | 131 | 137 [126, 151] | 32 | .53 |
Sex (n [%] male) | 55 (42) | 131 | 21 (64) | 33 | .042 |
Sodium (mEq/L) | 153 [151, 155] | 129 | 153 [150, 156] | 29 | .49 |
Total calcium (mg/dL) | 10.0 [9.6, 10.3] | 131 | 10.7 [10.3, 11.4] | 33 | <.001 |
Total protein (g/dL) | 7.8 [7.4, 8.1] | 131 | 7.6 [7.1, 8.3] | 33 | .31 |
USG | 1.017 [1.015, 1.020] | 81 | 1.018 [1.016, 1.020] | 21 | .25 |
Weight (kg) | 3.70 [3.15, 4.45] | 127 | 3.81 [3.18, 4.28] | 31 | .98 |
Abbreviations: ALP, alkaline phosphatase; BCS, body condition score; FGF23, fibroblast growth factor 23; MMS, muscle mass score; PTH, parathyroid hormone; SBP, systolic blood pressure; USG, urine specific gravity.