TABLE 3.
Selected clinicopathological baseline variables of initially normocalcemic cats that remain normocalcemic and those that develop persistent ionized hypercalcemia after diagnosis of azotemic chronic kidney disease.
| Variables | NCa‐NCa (n = 54) | n | NCa‐HCa (n = 25) | n | P |
|---|---|---|---|---|---|
| Median [25th, 75th percentile] | Median [25th, 75th percentile] | ||||
| Ionized calcium (mmol/L) | 1.31 [1.28, 1.33] | 54 | 1.32 [1.27, 1.35] | 25 | .29 |
| Age (years) | 15.4 [13.8, 16.7] | 53 | 14.3 [11.3, 17.2] | 24 | .31 |
| Albumin (g/dL) | 3.1 [2.9, 3.3] | 54 | 3.1 [2.9, 3.3] | 25 | .59 |
| ALP (U/L) | 30 [24, 40] | 54 | 27 [22, 39] | 25 | .63 |
| BCS (1‐9) | 4 [3, 5] | 54 | 5 [3, 6] | 25 | .17 |
| Chloride (mEq/L) | 119 [116, 120] | 54 | 117 [115, 119] | 25 | .22 |
| Creatinine (mg/dL) | 2.38 [2.10, 2.89] | 54 | 2.30 [2.05, 2.62] | 25 | .32 |
| FGF23 (pg/mL) | 523 [317, 874] | 49 | 322 [218, 812] | 25 | .38 |
| Globulin (g/dL) | 4.6 [4.3, 5.2] | 54 | 4.5 [4.2, 4.7] | 25 | .12 |
| HCO3 − (mEq/L) | 20 [18, 23] | 53 | 20 [19, 22] | 25 | .65 |
| MMS (0‐2) | 1 [1, 1] | 52 | 1 [1, 1] | 25 | .64 |
| PCV (%) | 35 [30, 36] | 54 | 35 [32, 42] | 25 | .031 |
| Venous pH | 7.35 [7.30, 7.38] | 54 | 7.35 [7.31, 7.38] | 24 | .48 |
| Phosphate (mg/dL) | 3.92 [3.51, 4.76] | 54 | 3.53 [3.09, 4.49] | 25 | .09 |
| Potassium (mEq/L) | 3.9 [3.6, 4.2] | 54 | 4.0 [3.5, 4.3] | 25 | .84 |
| PTH (pg/mL) | 20.6 [13.6, 39.7] | 54 | 11.4 [7.9, 34.0] | 22 | .10 |
| SBP (mmHg) | 133 [118, 142] | 54 | 132 [119, 147] | 24 | .69 |
| Sex (n [%] male) | 22 (41) | 54 | 10 (40) | 25 | 1 |
| Sodium (mEq/L) | 153 [151, 155] | 54 | 152 [149, 154] | 25 | .35 |
| Total calcium (mg/dL) | 9.9 [9.4, 10.2] | 54 | 10.0 [9.8, 10.4] | 25 | .08 |
| Total protein (g/dL) | 7.7 [7.4, 8.2] | 54 | 7.5 [7.2, 7.9] | 25 | .11 |
| Weight (kg) | 3.58 [3.06, 4.25] | 52 | 4.04 [3.06, 4.72] | 25 | .25 |
Abbreviations: ALP, alkaline phosphatase; BCS, body condition score; FGF23, fibroblast growth factor 23; MMS, muscle mass score; PTH, parathyroid hormone; SBP, systolic blood pressure; USG, urine specific gravity.