TABLE 4.
Univariable and multivariable time‐invariant Cox regression results identifying risk factors for incident persistent ionized hypercalcaemia in cats with azotaemic chronic kidney disease (n = 79).
| Predictors | HR (95% CI) | P |
|---|---|---|
| Univariable results | ||
| Ionized calcium (mmol/L × 10) | 1.37 (0.59‐3.15) | .46 |
| Total calcium (mg/dL) | 1.75 (0.96‐3.18) | .06 |
| Age (years) | 0.89 (0.76‐1.03) | .13 |
| BCS (1‐9) | 1.44 (1.11‐1.86) | .006 |
| Chloride (mEq/L) | 0.93 (0.83‐1.03) | .17 |
| Creatinine (mg/dL) | 0.49 (0.19‐1.24) | .13 |
| Phosphate (mg/dL) | 0.78 (0.53‐1.14) | .20 |
| Albumin (g/dL) | 1.82 (0.51‐6.54) | .36 |
| Globulin (g/dL) | 0.60 (0.31‐1.17) | .13 |
| Total protein (g/dL) | 0.67 (0.36‐1.26) | .22 |
| Sodium (mEq/L) | 0.97 (0.88‐1.07) | .53 |
| Potassium (mEq/L) | 0.99 (0.46‐2.16) | .99 |
| ln[FGF23 (pg/mL)] | 0.86 (0.60‐1.24) | .43 |
| ln[PTH (pg/mL)] | 0.68 (0.43‐1.06) | .09 |
| HCO3 − (mEq/L) | 1.03 (0.91‐1.17) | .67 |
| pH × 10 | 1.28 (0.57‐2.87) | .55 |
| Weight (kg) | 1.30 (0.92‐1.85) | .14 |
| ALP (U/L) | 1.00 (0.98‐1.02) | .88 |
| MMS (0‐2) | 1.75 (0.64‐4.77) | .27 |
| PCV (%) | 1.08 (1.01‐1.16) | .035 |
| SBP (mmHg) | 1.01 (0.98‐1.03) | .58 |
| Sex (male vs female) | 1.17 (0.52‐2.61) | .71 |
| Multivariable results | ||
| BCS (1‐9) | 1.44 (1.11‐1.86) | .006 |
Abbreviations: ALP, alkaline phosphatase; BCS, body condition score; FGF23, fibroblast growth factor 23; MMS, muscle mass score; SBP, systolic blood pressure.