TABLE 2.
Perorally administered corticosteroids and antiepileptic drugs during treatment, ITT population
| Total (n = 57) | Control [10 × 4 Gy] (n = 28) | SIB [10 × 4 Gy + 11% boost to the GTV] (n = 29) | |
|---|---|---|---|
| Prednisolone at the start of RT (n, %) | 53 (93%) | 25 (89%) | 28 (97%) |
| Dosage (mg/kg) a q24h | 0.60 (0.14‐2.00) | 0.60 (0.19‐2.00) | 0.59 (0.14‐1.34) |
| Prednisolone at the end of RT (n, %) | 53 (93%) | 25 (89%) | 28 (97%) |
| Dosage (mg/kg) a q24h | 0.54 (0.14‐2.00) | 0.52 (0.19‐2.00) | 0.55 (0.14‐1.50) |
| Antiepileptic drugs at the end of RT (n, %) | 30 (53%) | 14 (50%) | 16 (55%) |
| Phenobarbital (n, %); dosage (mg/kg) a q12h | 23 (40%); 2.50 (1.59‐3.78) | 11 (39%); 2.50 (1.70‐3.75) | 12 (41%); 2.62 (1.59‐3.78) |
| Levetiracetam (n, %), dosage (mg/kg) a q8h | 16 (28%); 17.95 (9.10‐28.40) | 7 (25%); 17.20 (13.10‐25.90) | 9 (31%); 18.70 (9.10‐28.40) |
| Imepitoin (n, %), dosage (mg/kg) a q12h | 3 (5%); 13.30 (11.90‐32.00) | 0 (0%); − | 3 (10%); 13.30 (11.90‐32.00) |
| Monotherapy (n, %) | 18 (32%) | 10 (36%) | 8 (28%) |
| >1 antiepileptic drug (n, %) | 12 (21%) | 4 (14%) | 8 (28%) |
a
Values expressed as median and range; q × h, every × hours.