TABLE 2.
Summary of population characteristics including complete blood count and serum biochemistry data from study entry
| Parameter | All dogs (n = 16) | Aspiration pneumonia (n = 12) | Bacterial pneumonia (n = 4) | P‐value | Adjusted P‐value |
|---|---|---|---|---|---|
| Age (years) | 4.3 ± 3.8 | 5.5 ± 3.7 | 0.8 ± 0.2 | <.01 | .02 |
| Bodyweight (kg) | 25.9 ± 16.3 | 24.0 ± 17.2 | 31.5 ± 13.6 | .4 | .56 |
| Sex (FI/FS/MI/MC) | 1/5/6/4 | 1/3/4/4 | 0/2/2/0 | .38 | .56 |
| APPLEfast score | 14 (11‐20) | 14 (11‐22) | 16 (12‐20) | .58 | .75 |
| Length of hospitalization (days) | 3 (2‐4) | 3 (2‐4) | 3.3 (1.3‐13.0) | 1.0 | 1.0 |
| Duration of antimicrobials (days) | 22.9 ± 10.2 | 20.7 ± 8.7 | 29.8 ± 12.7 | .25 | .47 |
| Antimicrobial drugs prescribed (n) | 3 (3‐4) | 3 (3‐4) | 4 (3‐6) | .06 | .25 |
| HCT (%) | 46.8 ± 7.9 | 48.9 ± 7.7 | 40.3 ± 4.3 | .02 | .15 |
| Hgb (g/dL) | 15.6 ± 2.6 | 16.4 ± 2.5 | 13.3 ± 1.4 | .01 | .13 |
| Leukocytes (×103/μL) | 13.5 ± 7.1 | 11.5 ± 6.3 | 19.7 ± 6.5 | .08 | .25 |
| Neutrophils (×103/μL) | 10.3 ± 6.1 | 9.0 ± 5.4 | 14.3 ± 7.2 | .24 | .47 |
| Bands (×103/μL) | 1.3 ± 1.4 | 1.1 ± 1.4 | 2.0 ± 1.4 | .31 | .51 |
| Lymphocytes (×103/μL) | 0.9 (0.4‐1.2) | 0.7 (0.3‐1.5) | 1.6 (0.8‐2.7) | .05 | .25 |
| Monocytes (×103/μL) | 1.0 ± 0.8 | 0.8 ± 0.7 | 1.7 ± 0.7 | .07 | .25 |
| Eosinophils (×103/μL) | 0.0 (0.0‐0.2) | 0.0 (0.0‐0.5) | 0.0 (0.0‐0.2) | .76 | .84 |
| Platelets (×103/μL) | 236 ± 96 | 249 ± 100 | 197 ± 79 | .32 | .51 |
| Albumin (mg/dL) | 3.4 ± 4.7 | 3.5 ± 0.5 | 3.1 ± 0.4 | .94 | .99 |
| ALT (U/L) | 60 (43‐90) | 67 (49‐98) | 38 (24‐77) | .11 | .26 |
| Bilirubin (total) (mg/dL) | 0.1 (0.0‐1.0) | 0.1 (0.0‐1.0) | 0.1 (0.0‐0.2) | .67 | .79 |
| BUN (mg/dL) | 11 (8‐17) | 12 (9‐19) | 9 (7‐10) | .09 | .26 |
| Cholesterol (mg/dL) | 252 (211‐267) | 254 (222‐282) | 224 (197‐251) | .13 | .28 |
| Creatinine (mg/dL) | 0.7 (0.6‐0.9) | 0.7 (0.6‐1.0) | 0.7 (0.4‐0.9) | .68 | .79 |
Note: Data are presented as mean ± SD for normally distributed data and median (IQR) for non‐normally distributed data. Comparisons between data from dogs with aspiration pneumonia and those with bacterial pneumonia were compared with t‐tests, Mann‐Whitney U tests or χ 2. Raw P‐values and those following adjustment for multiple comparisons using the Benjamini‐Hochberg false discovery rate method are presented. P‐values displayed in bold font remained significant at P < .05 after correction for multiple comparisons.