Table 1:
Characteristics of PDX models
| ID | Disease type | Karyotype | Mutations |
|---|---|---|---|
| 16–01 (34) | relapsed AML | CALM-AF10, complex karyotype | NF1, TP53, PHF6 |
| 17–14 (34) | tAML, relapsed | MLL-AF10, complex karyotype | KRAS |
| CBAM-68552 (35) | primary AML | MLL-AF6 | none detected |
| CPCT-0007 (36) | refractory AML | MLL-CALM | NRAS |
| CPCT-0027 (36) | primary AML | CBFA2T3-GLIS2 | NRAS, WT1 |
| DFAM-93240 (35) | primary AML | AML with inv(16) CBFB-MYH11 | TP53 |
| 2017–63 | relapsed, refractory AML | MNX1-ETV6 | none detected |
| 2017–94 | relapsed, refractory AML | complex karyotype | CDKN1A/B |