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. Author manuscript; available in PMC: 2024 Mar 1.
Published in final edited form as: Ann Surg. 2021 Dec 14;277(3):e592–e596. doi: 10.1097/SLA.0000000000005338

Table 3.

Comparison of Morbidity and Mortality by ISGLS Grade (n=1,646)

No ISGLS PHLF ISGLS A ISGLS B ISGLS C
n=1,202 n=285 n=106 n=53
CCI
median (IQR) 0 (0-20.9)* 8.7 (0-26.2)* 27.6 (20.9-34.8)* 100 (50.7-100)* p<0.001
CCI Category, N (%)
CCI: 0 674 (56.1) 138 (48.4) 0 (0) 0 (0)
CCI: 1-20 104 (8.7) 19 (6.7) 13 (12.9) 0 (0)
CCI: 20-40 369 (31.0) 110 (38.6) 76 (71.7) 7 (13.2)
CCI: 40-60 33 (2.8) 9 (3.2) 13 (12.3) 9 (17.0)
CCI: 60-80 2 (0.2) 0 (0) 0 (0) 1 (1.9)
CCI: 80-100 20 (1.7) 9 (3.2) 4 (3.8) 36 (67.9)
CCI > 40
OR (95% CI) - 1.41 (0.81-2.43) 3.98 (2.22-7.15) 137.04 (59.17-317.42) AUC=0.72
90-day mortality
OR (95% CI) - 1.75 (0.80-3.84) 2.66 (0.98-7.16) 113.58 (55.59-232.07) AUC=0.78
*

Dunn’s multiple comparison test with Bonferroni adjustment revealed statistically significant differences between this value relative to all other categories.

ISGLS: International Study Group of Liver Surgery; PHLF: post-hepatectomy liver failure; CCI: comprehensive complication index; IQR: interquartile range; OR: odds ratio; CI: confidence interval