Table 4.
Association between Preoperative Liver Pathology and Grades B/C PHLF (n=1646)
| Univariate OR | 95% CI | Adjusted OR a | 95% CI | |
|---|---|---|---|---|
| Tumor histology | ||||
| CRLM | 9.78 | (2.33, 40.50) | 3.34 | (0.67, 16.55) |
| HCC | 8.24 | (1.98, 34.22) | 2.40 | (0.50, 11.58) |
| CCC | 17.82 | (4.26, 74.59) | 6.38 | (1.37, 29.70) |
| Benign | 1.43 | (0.24, 8.65) | 1.16 | (0.18, 7.44) |
| Other malignancy | 7.50 | (1.61, 34.93) | 2.12 | (0.40, 11.34) |
| Liver histology | ||||
| Steatosis | 1.85 | (1.20, 2.85) | 1.30 | (0.80, 2.13) |
| Fibrosis/Cirrhosis | 2.26 | (1.52, 3.37) | 1.93 | (1.15, 3.22) |
| Chemotherapy | 0.94 | (0.58, 1.51) | 0.60 | (0.32, 1.09) |
| NALFD | 2.84 | (1.55, 5.18) | 2.31 | (1.16, 4.62) |
a
Covariates: age, sex, year of operation, ASA, Charlson Comorbidity Index, segments resected, operative approach, previous abdominal surgery
OR: odds ratio; CI: confidence interval; CRLM: colorectal liver metastasis; HCC: hepatocellular carcinoma; CCC: cholangiocarcinoma; NAFLD: non-alcoholic fatty liver disease