Table 1.

Summary of main indication for cancer types

Site	Patient setting	RT management	RT schedules	COVID + (asymptomatic/mild symptomatic)	COVID + (symptomatic)
Lung cancer [72–82]	General	Increase HFRT Increase SBRT		Continue RT(CT) with close monitoring of clinical conditions	Postpone after confirmed healing Interrupt or preliminarily terminate ongoing treatments
	NSCLC	Delay post-operative RT Avoid twice-daily treatments
	NSLC (early stage)	Increase SBRT	50–60 Gy in 5 fr (central tumors) 48 Gy in 4 fr (adjacent/contact with chest wall)
	SCLC	Delay PCI Consider delivering PCI during concurrent RT(CT)
Hematological cancer [83]	General	Shorten RT course
	Palliative	Omission RT treatments		–
	Localized low-grade	Omission RT for completely excised Delay for asymptomatic patients		Delay RT
	Localized nodular LH	Omission RT for completely excised Delay for asymptomatic patients
	Diffuse large B/aggressive LNH	Omission RT for consolidation
Head & Neck [72, 84–93]	General	Increase HFRT		Continue RT(CT) with close monitoring of clinical conditions Use surgical mask with immobilization setup
Prostate [94–99]	General	Increase HFRT Consider starting RT up to 6 months after OT
	Low-risk	Increase HFRT Increase SBRT	36.25 Gy in 5 fr twice-week
Gastrointestinal [98, 100–110]	Esophageal cancer		40 Gy in 15 fr
	Inoperalble Cholangiocarcinoma	Consider SBRT
	Pancreatic cancer	Consider SBRT in inoperable LAPC
	Anal cancer	Increase HFRT	36/40 Gy in 20 fr to elective volume; 50 Gy in 20 fr to primary tumor with SIB
	Liver cancer	Carbon ION RT for unresectable disease Consider SBRT for Hepato Cellular Carcinomas	30–60 Gy in 3–5 fr
	Rectal cancer	Prefer short course treatments
Skin [112–116]	General	Delay or omit adjuvant RT Consider HFRT Consider contact skin RT
Breast [98, 117–121]	General	Delay or omit adjuvant RT in older adult EBC Consider HFRT
Soft tissues – Sarcomas [122]	General	Consider HFRT	30 Gy in 10 fr 30 Gy in 5 fr 28 Gy in 8 fr 25 Gy in 5 fr
Gynecological [123, 124]	General	Consider HFRT
	Uterine cancer	Do not exceed 6 weeks after surgery for adjuvant RT

RT radiation therapy, HFRT Hypofractionated radiation therapy, SBRT Stereotactic body radiation therapy, NSCLC Non-small cell lung cancer, SCLC Small cell lung cancer, PCI prophylactic cranial irradiation, LH Hodgkin lymphomas, LNH Non-Hodgkin lymphomas, LAPC Locally advanced pancreatic cancer, SIB simultaneous integrated boost, EBC Early breast cancer