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. 2022 Jul 16;2022:3678441. doi: 10.1155/2022/3678441

Table 2.

Univariate and multivariate Cox regression analyses of PFS and OS.

Parameters PFS OS
Univariate analysis Multivariate analysis Univariate analysis Multivariate analysis
Hazard ratio (95% CI) P value Hazard ratio (95% CI) P value Hazard ratio (95% CI) P value Hazard ratio (95% CI) P value
Type of treatment 0.347 0.319
 CCRT 1 (reference) 1 (reference)
 RT 1.61 (0.85–1.58) 1.45 (0.70–3.03)

Clinical TNM classification 0.167 0.361
 II 1 (reference) 1 (reference)
 III 0.80 (0.58–1.10) 0.71 (0.34–1.49)

N stage 0.167 0.361
 N0 1 (reference) 1 (reference)
 N1-2 1.56 (0.83–2.93) 1.41 (0.67–2.98)

Local recurrence 0.005 0.006
 No 1 (reference) 1 (reference)
 Yes 2.57 (1.33–4.94) 2.83 (1.35–5.91)

Distant metastasis 0.077 0.537
 No 1 (reference) 1 (reference)
 Yes 1.81 (0.94–3.48) 1.27 (0.60–2.69)

Duration of treatment 0.058 0.031
 ≤6 weeks 1 (reference) 1 (reference)
 >6 weeks 0.54 (0.28–1.02) 0.42 (0.19–0.92)

Diseases related death 0.001 0.001 0.001 0.000
 No 1 (reference) 1 reference 1 (reference) 1 (reference)
 Yes 2.89 (1.51–5.55) 2.89 (1.51–5.55) 3.82 (1.77–8.24) 4.96 (2.19–11.26)

Dose of irradiation 0.094 0.017 0.071 0.005
 ≤54 Gy 1 (reference) 1 (reference) 1 (reference) 1 (reference)
 >54 Gy 0.47 (0.19–1.14) 0.33 (0.13–0.82) 0.40 (0.15–1.08) 0.21 (0.07–0.62)