Table 2.

Significant radiomic features resulted in comparison between responders (PFS ≤ 11) and non-responders (PFS > 11) NETs in internal and external cohorts

Radiomic features	PFS ≤ 11	PFS > 11	P Internal cohort	Bonferroni correction	PExternal cohort	Bonferroni correction
Arterial phase	Mean ± SD	Mean ± SD
First Order_10Percentile	49.93 ± 13.19	38 ± 12.07	0.03	–	0.002	–
First Order_Mean	70.12 ± 12.79	59.76 ± 9.85	0.04	–	0.002	–
First Order_Median	70 ± 12.67	59.9 ± 9.62	0.04	–	0.002	–
First Order_ RootMeanSquared	76.82 ± 15.41	63.27 ± 9.40	0.02	–	0.0001	–
GLCM_Correlation	0.29 ± 0.21	0.17 ± 0.05	0.001	–	< 0.0001	< 0.0001
GLCM_Imc1	− 0.07 ± 0.16	− 0.03 ± 0.01	0.004	–	< 0.0001	< 0.0001
GLCM_Imc2	0.32 ± 0.23	0.21 ± 0.06	0.01	–	< 0.0001	< 0.0001
GLCM_MCC	0.42 ± 0.3	0.28 ± 0.07	0.04	–	< 0.0001	< 0.0001
GLSZM_LargeAreaLowGrayLevelEmphasis	191,313.61 ± 228,501.47	317,486.48 ± 588,025.78	< 0.0001	< 0.0001	0.04	–
Portal phase
Shape_SurfaceVolumeRatio	0.07 ± 0.01	0.06 ± 0.008	0.04	–	< 0.0001	< 0.0001

Bold values denote statistical significance

PFS Progression-free survival, SD Standard deviation, GLCM Gray-level co-occurrence matrix, GLSZM Gray-level size zone matrix