Table 3.
Performance of radiomic parameters in comparison between responders and non-responders tested by using receiver operating characteristic (ROC) curve in internal cohort
| Radiomic features | PFS 11 vs PFS > 11 | ||||
|---|---|---|---|---|---|
| Arterial phase | Sensitivity | Specificity | AUC | Criterion | P |
| First Order_10Percentile | 78% | 80% | 0.77 | > 44 | 0.01 |
| First Order_Mean | 71.4% | 90% | 0.76 | > 65.6 | 0.02 |
| First Order_Median | 71.4% | 90% | 0.76 | > 66 | 0.01 |
| First Order_ RootMeanSquared | 78.6% | 80% | 0.81 | > 66.9 | 0.001 |
| GLCM_Correlation | 78.6% | 80% | 0.86 | > 0.21 | < 0.0001 |
| GLCM_Imc1 | 78.6% | 80% | 0.84 | -0.04 | < 0.0001 |
| GLCM_Imc2 | 42.9% | 100% | 0.76 | > 0.29 | 0.01 |
| GLCM_MCC | 50% | 100% | 0.73 | > 0.42 | 0.03 |
| GLSZM_LargeAreaLowGrayLevelEmphasis | 35.7% | 100% | 0.58 | 22,113.22 | 0.52 |
| Portal phase | |||||
| Shape_SurfaceVolumeRatio | 71.4% | 70% | 0.74 | > 0.06 | 0.01 |
Bold values denote statistical significance
*PFS Progression-free survival, AUC Area under the curve, GLCM Gray-level co-occurrence matrix, GLSZM Gray-level size zone matrix