Figure 3. A proteome-informed genetic screen to identify wiring executors of Acj6.
(A) Schematic of the genetic screen and quantification. Dendrite innervation of each glomerulus was scored into three categories: strong, weak, and none. Scorer was blind to genotypes.
(B) Confocal images showing dendrite innervation patterns of adPN−GAL4+ PNs (green) in controls and when acj6 or candidate genes were knocked down by RNAi. Blue, N-cadherin (NCad) staining highlight the glomeruli. Glomeruli with decreased PN dendrite innervation are circled in red while ectopically targeted glomeruli are circled in white. Arrowheads point to the glomeruli exhibiting mistargeting phenotypes.
Scale bars, 20 μm. D, dorsal; L, lateral.
See also Figures S3 and S4.