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. Author manuscript; available in PMC: 2023 Aug 1.
Published in final edited form as: J Neural Transm (Vienna). 2022 Jun 26;129(8):1001–1009. doi: 10.1007/s00702-022-02523-3

Table 4:

Relationship between MGN [18F]FEOBV binding in the medial geniculate nucleus (MGN) and the presence of imbalance, falls and FoG in persons with PD (n=54).

VAChT region PIGD status subgroup model Age Duration Gender Striatal dopamine
[11C]DTBZ PET
Total model
MGN Imbalance status
F=5.20, P=0.027
(9.6%* lower in HY ≥2.5 stage stage)
F=3.9, P=0.054 F=0.01, P=0.91 F=2.2, P=0.14 F=3.2, P=0.08 R2=0.28, F=3.6, P=0.008
MGN Fall status
F=5.9, P=0.019
(9.9%* lower in fallers)
F=6.2, P=0.017 F=0.2, P=0.69 F=0.8, P=0.39 F=1.8, P=0.18 R2=0.29, F=3.8, P=0.006
MGN FoG status
F=13.5, P=0.0006
(22%* lower in freezers)
F=3.6, P=0.07 F=0.7, P=0.41 F=0.8, P=0.37 F=0.04, P=0.84 R2=0.38, F=5.7, P=0.0004

ANCOVA F-values (with levels of significance) are listed for the group effects and age, duration of disease, gender, striatal dopamine [11C]DTBZ PET binding and total model effects. FoG = freezing of gait.

*

covariate adjusted