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. 2022 Jun 10;23(14):e202200180. doi: 10.1002/cbic.202200180

Figure 7.

Figure 7

Predicted binding mode in drHDAC10 (PDB ID 6UHU) of pan‐inhibitors abexinostat (12), quisinostat (11) and panobinostat (9): a) Abexinostat (colored salmon), b) quisinostat (colored teal), and c) panobinostat (colored green). Side chains of binding site residues are shown as white sticks and the catalytic zinc ion as orange spheres. Hydrogen bonds and salt bridge interactions are depicted as blue‐dashed lines and coordination of the zinc ion by the ligand as yellow‐dashed lines.