表 1.

各组T细胞体外杀伤活性比较

Comparison of cytotoxicity among T cells, CAR-T and NISCAR-T cells at different effector-target (E: T) ratios (%, Mean±SD)

E: T ratio	T cells	CAR-T	NIS-CAR-T
Each experiment was repeated three times.
24 h
0.5:1	1.69±0.44	7.64±0.95	4.47±0.49
1:1	6.52±2.05	15.75±0.72	11.21±0.45
2:1	12.97±0.96	35.35±2.60	20.83±1.37
4:1	20.97±1.14	48.69±2.31	42.13±1.78
48 h
0.5:1	6.19±0.22	13.04±1.57	12.10±0.96
1:1	11.96±0.96	44.02±2.86	40.25±1.18
2:1	29.18±2.33	59.41±1.08	50.07±3.38
4:1	36.69±1.04	76.66±0.27	76.56±1.57
72 h
0.5:1	17.36±2.21	41.90±0.34	38.11±1.53
1:1	22.24±0.47	59.28±4.14	55.43±2.86
2:1	33.81±1.85	83.83±1.83	83.49±1.98
4:1	44.29±0.80	96.35±1.91	91.01±3.35