Table 3.
Comparison of baseline characteristics after PSM in two groups
| Variables | Anastomotic leakage n = 35 |
Non-anastomotic leakage Statistical values n = 35 |
p | ||
|---|---|---|---|---|---|
| Age | (< 60/ ≥ 60) | 5/30 | 7/28 | 1.867 | 0.172 |
| Sex | (Male/female) | 24/11 | 25/10 | 0.068 | 0.794 |
| BMI (Kg/m2) | 23.6 ± 2.3 | 22.9 ± 2.5 | 0.086 | 0.700 | |
| Smoking | (No/Yes) | 28/7 | 26/9 | 0.324 | 0.569 |
| Alcohol | (No/Yes) | 30/5 | 32/3 | 0.565 | 0.452 |
| Abdominal operation | (No/Yes) | 27/8 | 27/8 | 0 | > 0.05 |
| T2DM | (No/Yes) | 33/2 | 31/4 | 0.729 | 0.393 |
| Cardiovascular disease | (No/Yes) | 34/1 | 33/2 | 0.348 | 0.555 |
| Hypertension | (No/Yes) | 25/10 | 26/9 | 0.072 | 0.788 |
| COPD | (No/Yes) | 31/4 | 33/2 | 0.729 | 0.393 |
| Hepatitis | (No/Yes) | 34/1 | 34/1 | 0 | > 0.05 |
| Kidney disease | (No/Yes) | 34/1 | 34/1 | 0 | > 0.05 |
| Hyperlipidemia | (No/Yes) | 35/0 | 34/1 | 1.014 | 0.314 |
| Transfusion history | (No/Yes) | 35/0 | 35/0 | 0 | > 0.05 |
| Bowel preparation | (No/Yes) | 0/35 | 0/35 | 0 | > 0.05 |
| Hemoglobin (g/L) | (< 90/ ≥ 90) | 15/20 | 14/21 | 0.059 | 0.808 |
| Tumor location | Transverse colon descending, sigmoid colon rectum | 2/4/29 | 0/2/33 | 2.925 | 0.232 |
| NRS2002 | (< 3/ ≥ 3) | 9/26 | 10/25 | 0.072 | 0.788 |
| LCR | (≤ 6000/ > 6000) | 32/3 | 11/24 | 26.589 | < 0.01 |
| ASA score | (I/II/III/IV) | 14/16/5/0 | 16/16/2/1 | 2.419 | 0.490 |
| ECOG score | (0/1/2/3/4) | 2/26/7/0 | 8/20/5/2 | 6.716 | 0.082 |
| Total bilirubin (μmol/L) | 11.1 ± 5.2 | 13.1 ± 6.7 | 0.002 | 0.194 | |
| Direct bilirubin (μmol/L) | 3.3 ± 1.6 | 2.7 ± 1.4 | 0.356 | 0.127 | |
| ALT (IU/L) | 17.6 ± 10.1 | 15.5 ± 9.5 | 0.153 | 0.364 | |
| AST (IU/L) | 18.0 ± 8.2 | 18.3 ± 8.5 | 0.083 | 0.887 | |
| Prealbumin (g/L) | 0.18 ± 0.05 | 0.21 ± 0.04 | 0.057 | 0.105 | |
| Albumin (g/L) | 37.9 ± 4,0 | 38.1 ± 4.4 | 0.461 | 0.898 | |
| Urea (mmol/L) | 4.77 ± 2.0 | 5.5 ± 4.0 | 0.249 | 0.284 | |
| Creatinine (μmol/L) | 77.9 ± 15.9 | 87.1 ± 65.9 | 1.444 | 0.424 | |
| Uric acid (μmol/L) | 295.0 ± 78.9 | 289.1 ± 76.3 | 0.055 | 0.750 | |
| White blood count(109/L) | 6.6 ± 2.8 | 5.7 ± 1.4 | 5.966 | 0.080 | |
| Neutrophil count (109/L) | 4.3 ± 2.7 | 3.4 ± 1.3 | 4.565 | 0.085 | |
| Lymphocyte count (109/L) | 1.5 ± 0.7 | 1.5 ± 0.6 | 0.995 | 0.989 | |
| Hematocrit (%) | 34.5 ± 5.1 | 32.6 ± 6.1 | 1.935 | 0.145 | |
| Platelet count (109/L) | 208.7 ± 93.4 | 212.9 ± 77.4 | 0.047 | 0.835 | |
| APTT(s) | 32.6 ± 4.5 | 33.6 ± 4.6 | 0.154 | 0.361 | |
| PT(s) | 11.3 ± 0.9 | 11.3 ± 0.8 | 1.019 | 0.937 | |
| INR | 0.99 ± 0.07 | 0.98 ± 0.07 | 0.037 | 0.619 | |
BMI body mass index, ASA American Society of Anesthesiologists, ECOG Eastern Cooperative Oncology Group, COPD Chronic Obstructive Pulmonary Disease, NRS2002 Nutritional Risk Screening 2002, LCR Lymphocyte-C-reactive protein Ratio, ALT alanine aminotransferase, AST aspartate aminotransferase, T2DM type 2 diabetes mellitus, APTT activated partial thromboplasin time, PT prothrombin time, INR international normalized ration