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. Author manuscript; available in PMC: 2022 Jul 24.
Published in final edited form as: J Med Chem. 2021 May 11;64(10):6608ā€“6620. doi: 10.1021/acs.jmedchem.0c01926

Figure 2. Trichomonacidal activity and human cytotoxicity of FDA-approved and related gold(I) complexes.

Figure 2.

The activity of the indicated gold(I) complexes against T. vaginalis F1623 (pEC50, green bars) and human Hela cells (pCC50, red bars) were determined in 24ā€“48 h growth and survival assays. Results are shown as mean + SEM (nā‰„3 independent experiments). Selectivity index (SI) was calculated as CC50/EC50. The dashed line depicts the assay sensitivity.