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. 2022 Jun 22;7(12):e148990. doi: 10.1172/jci.insight.148990

Figure 4. Lymphoid cell subtypes of human GBM are identified in the QPP model.

Figure 4

Clustering at a resolution of 0.65 to reveal lymphoid subtypes in the QPP mouse model tumor or human GBM. UMAPs of immune constituents from (A) QPP-derived tumor (n = 6) and (B) patient glioma (n = 15) samples, showing clusters of lymphoid subtypes and representative markers for the following populations: T cells (Cd3d, Cd3e, and Cd3g as well as CD3D, CD3E, and CD3G); NK cells (Klrd1, Nkg7, and Nktr as well as KLRD1, NKG7, and NKTR; and B cells (Cd79a, Cd79b, and Ms4a7 as well as CD79A, CD79B, and MS4A7.