Fig. 2.

Analysis of immune mediators of COVID-19 hospitalized patients evolving with and without AKI. Circulating levels of (A) chemokines, (B) pro-inflammatory cytokines, (c) anti-inflammatory cytokines and (D) growth factors were assessed by a multiplex assay. Data is shown as median ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001 indicate comparison between groups (No AKI vs. AKI) in each time point (t test/Mann-Whiney test). P-values on horizontal bars indicate the comparison of time points (early vs. follow-up samples) for each group - blue lines for “No AKI” and red lines for “AKI” - (paired t test/Wilcoxon).