Table 1.
Patients’ demographics and baseline characteristics by study group and in the overall population
| Characteristic | BOT group (N = 253) | BB group (N = 78) | Overall population (N = 331) |
|---|---|---|---|
| Gender, N (%) | |||
| Male | 155 (61.3) | 37 (47.4) | 192 (58) |
| Female | 98 (38.7) | 41 (52.6) | 139 (42) |
| Age, years [mean (SD)] | 67.2 (10.0) | 67.4 (10.5) | 67.2 (10.1) |
| Diabetes characteristics | |||
| Duration from first diagnosis, years [median (IQR)] | 14.2 (8.3–20.8) | 16.1 (11.1–21.1) | 14.8 (8.7–21.0) |
| Age at diagnosis, years [mean (SD)] | 51.7 (10.9) | 50.3 (12.1) | 51.3 (11.2) |
| HbA1c, % [mean (SD)] | 8.5 (1.4) | 8.2 (1.7) | 8.4 (1.5) |
| Major diabetic complications, N (%) | |||
| None | 132 (52.2) | 33 (42.3) | 165 (49.8) |
| Diabetic macroangiopathy | 62 (24.5) | 26 (33.3) | 88 (26.6) |
| Diabetic nephropathy | 47 (18.6) | 23 (29.5) | 70 (21.1) |
| Diabetic retinopathy | 41 (16.2) | 16 (20.5) | 57 (17.2) |
| Diabetic neuropathy | 18 (7.1) | 15 (19.2) | 33 (10.0) |
| Concomitant conditions (specification), N (%) | |||
| With concomitant conditions | 205 (81.0) | 72 (92.3) | 277 (83.7) |
| Hypertension | 152 (74.1) | 53 (73.6) | 205 (74.0) |
| Dyslipidemia | 126 (61.5) | 43 (59.7) | 169 (61) |
| Symptomatic peripheral vascular disease | 27 (13.2) | 7 (9.7) | 34 (12.3) |
| Symptomatic coronary heart disease | 14 (6.8) | 4 (5.6) | 18 (6.5) |
| Symptomatic heart failure | 4 (2.0) | 3 (4.2) | 7 (2.5) |
| Stroke | 4 (2.0) | 1 (1.4) | 5 (1.8) |
| Other | 44 (21.5) | 24 (33.3) | 68 (24.5) |
OAD oral antidiabetic drug, BOT basal insulin ± OAD, BB basal insulin + bolus insulin ± OAD, SD standard deviation, IQR interquartile range, HbA1c glycated hemoglobin